ASU Roybal Center

ASU Roybal Center seeks applications to conduct NIH Stage 0-IV clinical trials that will develop and test mechanisms of behavioral change (MoBC)-driven and technology-enabled behavioral and lifestyle interventions for older adults living alone with cognitive decline.

Please join us for an informational webinar relevant to your application. View details and register here.

Four 2-year trials will be funded, with total funding up to $180,000 (direct + indirect costs) per trial. All awards expected to begin on June 1, 2026 (pending NIA approval). Applicants are strongly encouraged to seek indirect cost (IDC) waivers from their institutions to maximize available direct costs. A one-year no-cost extension may be considered.

These trials should test the ASU Roybal Center’s Conceptual Framework (Exhibit 1) with rigorous design to secure future funding (e.g.,NIH R01) to advance to the next Stage. 

The awards are for Early Stage Investigators (ESIs) as defined by the NIH, mid-career and established investigators across the U.S. Collaboration with experts in behavioral and lifestyle interventions, including with Center faculty, is encouraged but not required. 

Applications will be evaluated on seven criteria:

1. Significance of the problem for older adults living alone with cognitive decline
2. Ability to test ASU Roybal Center’s Conceptual Framework
3. Methodological rigor
4. Strength and novelty of the intervention
5. Potential to advance to the next Stage and future funding

6. Enrollment of populations with health disparities

    

7. Qualifications of the investigator team

Step 1: Letter of Intent (LOI) Application

Due Date: October 15,2025

Prior to submitting LOI applications, a consultation with ASU is strongly encouraged. Please contact Kristi Spieleder at [email protected] to schedule a consultation meeting. 

First fill out this initial applicant information form. Following completion of this form, you will receive a link to the LOI application where you will be asked for the following: 

1. Applicant Information 
2. PI NIH Biosketch 
3. Project Details 

4. Proposed Project Duration

    

Step 2: Full Proposal Application

Due Date: January 5, 2026 

If an LOI is accepted, applicants are encouraged to schedule the following consultations:

• Statistical Consultation: Applicants may elect to receive a complimentary statistical consultation on study design through the Roybal Coordinating Center. If interested in statistical consultation, please contact [email protected].

Applicants must submit a full proposal that includes the following: 

1. Applicant Information 
2. PI and Co-I NIH Biosketch 
3. Project Details 
4. Detailed Budget and Budget Justification 

For additional information and questions relating to ASU's application process, please email Kristi Spieleder at [email protected]. For logistical support in completing the application forms, please contact the Northwell Roybal Coordinating Center at [email protected].