Inflammatory mediators and beta-cell function among obese Latino youth with prediabetes
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Armando Pena (PhD student)
Gabe Shaibi; Micah Olson, MD
National Institute of Diabetes and Digestive and Kidney Disease
This study aims to examine the effect of lifestyle intervention on pro- and anti-inflammatory mediators in 79 obese Latino youth with prediabetes as compared to a usual care control group of 38 obesity- and glycemia-matched Latino youth. Understanding how changes in pro- and anti-inflammatory markers relate to changes in beta-cell function is important to identify specific mechanisms that can be targeted in future studies.